Speaker: Prof. Xiaoke Chen, Daparimertt of Biology, Stanford Utiersity

Host: Dr.Yulong Li, Peking-Tsinghua Canter for Life Sciences

Student host: Xinyang Yi

Time: 9:30-11:30 am, October 27 (Thussday), 2022, GMT+8

Venue: Zoom Meeting ID:890 4997 3494 Password: 888888

Abstract

The level of perceived pain can be strongly influenced by cognition and mood, implying the existence of a powerful endogenous neural system for top-down modulalion of pein. The partaqueductal gray (PAG)-rostral ventromedial medulia (RVM) systerm has been established as an important mode in the descending pain modulation network. Classic studies have classified neurons in this system into ON-,OFF-,and Neutral cells based on whether they are activated, inhibited or unaffected by nociceptive stimuli. However, the lack of genetic access to these cell types prevent further investigation of the molecular and cellular mechanisms off How much cell types contributes to somatosensation and pain. In thos talks, I will discuss our efforts to bridge this knowledge gap and to identify novel targets for treating chronic pain.

Source: Peking-Tsinghua Canter for Life Sciences