Speaker: Guozhen Liu, The Chinese University of Hong Kong, Shenzhen

Time: 20:00-21:30 pm, Februray 28, 2023, GMT+8

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Abstract:

Cytokines are signalling molecules between cells in immune system. As immune mediator, cytokines perform context-dependent functions and can exert opposing effects depending on the stage of inflammation, with important implications in diseases diagnosis and management. There has been a fast-growing market and academic interest in developing novel diagnosing devices driven by the increasing demand for continuous monitoring of inflammation in healthcare. By integrating with nanotechnology and biotechnology, biosensors as the analytical devices for the detection of an analyte, that combines a biological component with a physicochemical detector, have demonstrated huge potential for cytokine detection. In this talk, Liu will summarize her recent research highlights on development of advanced sensing technologies which can be integrated in microfluidic paper based analytical devices, soft wearable devices and implantable in vivo devices for monitoring of cytokines. She will discuss strategies on quantifying neuroinflammation, and its contribution to early diagnosis of chronic diseases such as Parkinson’s disease.

Biography:

Guozhen Liu, an associate professor of Biomedical Engineering, School of Medicine, the Chinese University of Hong Kong, Shenzhen, is leading a research team working on Integrated Devices and Intelligent Diagnostics (ID2). Her team focuses on interdisciplinary and translational research to develop cutting-edge technologies applicable for point-of-care diagnostics, microfluidic biochips, and medical devices to accurately diagnose, manage and prevent chronic diseases such as diabetes, Parkinson's disease, etc. Prof Liu has published >150 peer-reviewed journal papers, 3 book chapters and lodged 16 patents with a current h-index of 47. Prof Liu was awarded the prestigious Australian Research Council Future Fellowship (2016), the Academic Excellence Award for transdisciplinary research (2017) ，George Sweet Award for Women in Quantitative Biomedical Science (2020)，and the world’s top 2% scientists in Analytical Chemistry （2022）. Prof Liu’s research career has alternated between industrial and academic research. Prof Liu’s industrial experience includes over four years spent as R&D Manager, China for AgaMatrix Inc. to make medical devices for diabetes. Through cooperation with international biotechnology companies, such as AstraZeneca, BioLegend, AgaMatrix, Regeneus, etc., she has accumulated extensive experience in industry, education and research. Currently, Prof Liu is serving as a Specialty Chief Editor of Frontiers in Bioengineering and Biotechnology.     

Source: SRMC